COSMIIC Pulse Generator (PG4)

The PG4 is a four-channel implantable pulse generator for electrical stimulation of nerve and muscle tissue. It delivers programmable monopolar stimulation through four independent electrodes, using the device case as the common return path.

How it works

The PG4 receives stimulation parameters over the CANopen network from the Power Module. Its Atmel AT90CAN128 processor converts control signals into precise charge-balanced stimulus pulses according to pre-programmed patterns or real-time commands. The SYNC message from the PM controls pulse frequency.

Three independent failsafe mechanisms protect against overstimulation:

  1. Hardware limits on total charge per pulse
  2. Software limits on stimulation parameters
  3. Magnetic shutdown switches in both PG4 and PM

Hardware

Parameter Value
Processor Atmel AT90CAN128 (8-bit AVR)
Channels 4 independent monopolar
Pulse Width 1–255 microseconds
Pulse Amplitude 0–20 mA
Inter-Phase Interval 5–100 μs (default 50)
Frequency 1–50 Hz (via SYNC period)
Network CANopen, 4 ports (1 in + 3 out)
Power Network-powered from PM
Case Titanium with epoxy header
Placement Extremities (upper arm, forearm)

Stimulation Modes

  • Direct PM parameter setting — ~50 Hz update, up to 24 channels
  • SDO direct setting — ~4 Hz for 12 channels, ~50 Hz single channel (recommended for testing)
  • Pattern-based lookup tables — preloaded, up to 48 patterns per PG4 (recommended for permanent systems)

MATLAB Control

nnp.networkOn;
nnp.setSync(50);            % 50ms = 20 Hz
nnp.enterTestStim;
nnp.write(node, '3212', ch, [PW, PA*10]);  % pulse width, amplitude
nnp.write(node, '3212', ch, [0, 0]);       % stop
nnp.enterWaiting;

Build

Source: COSMIIC-Community/Implantables-PG4-Hardware (Aug 2025)

EDA: Altium Designer (PcbDoc + SchDoc format)

Firmware: COSMIIC-Community/Implantables-PG4-App (C, AVR toolchain)

Source

All design files are open source under CERN-OHL-P-2.0 (hardware) and MIT (firmware).

Files

File Description
cosmiic-pg4-altium-project.zip Altium project — PcbDoc, PcbLib, 8-page schematic (SchDoc), PrjPCB
cosmiic-pg4-gerbers.zip Gerber fabrication files
cosmiic-pg4-schematic.pdf Full schematic PDF (8 pages)
cosmiic-pg4-assembly.step Complete mechanical assembly STEP (titanium case, headers, capthroughs)
cosmiic-pg4-bom.xlsx Bill of Materials (Excel)

Altium Project Structure

The Altium project (PG4D) contains:

  • PCB layout (PG4D.PcbDoc) + component library (PG4D.PcbLib)
  • 8-page schematic covering stimulation DACs, current sources, CAN interface, AVR MCU, safety circuits, and electrode connectors

NSF Relevance

The PG4 is a four-channel implantable stimulator module capable of delivering programmable monopolar stimulation through four independent electrodes using the device case as the return path. Powered and networked through a single cable, the PG4 incorporates an Atmel AT90CAN128 MCU for precise waveform generation and incorporates triple-layer failsafe protections, including hardware charge limits, software safety checks, and magnetic shutdown control.

Science Drivers

implantable_healthcare

Created by: adonis
Version: v1
Category: stimulation

Files